Diosmin, a powerful flavonoid found in citrus fruits, offers a range of health benefits. From treating Piles and varicose veins to improving blood circulation and reducing inflammation, diosmin has become a popular natural therapy. In this article, we will explore the benefits, recommended dosage, potential side effects, and alternative treatments associated with diosmin.

What is Diosmin?

Diosmin is a flavonoid primarily found in citrus fruits. Flavonoids are plant compounds known for their antioxidant properties, which help protect the body against inflammation and free radicals. Diosmin was first discovered in the figwort plant in 1925 and has been used since 1969 to treat various conditions such as Piles, varicose veins, venous insufficiency, leg ulcers, and circulatory issues. It is believed to reduce inflammation and restore normal blood flow, particularly in individuals with venous insufficiency.

Today, diosmin is commonly derived from another flavonoid called hesperidin, which is abundant in citrus fruits, especially orange rinds. Diosmin is often combined with other flavonoids like disomentin, linarin, and isorhoifolin, forming a supplement known as micronized purified flavonoid fraction (MPFF). In the market, you may find diosmin under different brand names such as Diovenor, Daflon, Barosmin, citrus flavonoids, Flebosten, Litosmil, or Venosmine.

Benefits and Uses

Diosmin is most commonly used to treat blood vessel disorders, particularly Piles and chronic venous insufficiency (CVI). Piles are swollen veins near the anus, while CVI refers to blocked veins in the legs. Diosmin is also utilized for conditions such as varicose veins, blood clots, retinal hemorrhage, venous leg ulcers, and venous stasis.

Numerous studies have demonstrated the effectiveness of diosmin in treating internal and external Piles. It has been shown to reduce symptoms such as itching, bleeding, and discharge associated with Piles. Additionally, diosmin aids in the post-operative recovery following hemorrhoidectomy, the surgical removal of Piles. However, it is important to note that diosmin may be more effective in the early stages of Piles disease.

Diosmin has also been found to improve symptoms associated with chronic venous disease, including leg ulcers, edema, varicose veins, tingling sensation, and general quality of life. By reducing inflammation, improving vein health, and enhancing blood and lymphatic circulation, diosmin provides relief from the symptoms of CVI. It has shown positive results in reducing leg heaviness, swelling, cramps, and restless leg syndrome. However, it's advisable to consult a healthcare professional for personalized guidance on the use of diosmin for chronic venous disease.

In addition to Piles and CVI, diosmin has been explored for its potential benefits in managing back pain, lymphedema, varicocele, minor bleeding, pelvic pain, and rosacea. While some studies have shown positive results, larger studies are needed before making widespread recommendations for these conditions.

Side Effects and Precautions

Diosmin is generally considered safe and is available as an over-the-counter supplement. However, some individuals may experience rare side effects such as stomach pain, diarrhea, headaches, dizziness, skin rash, hives, muscle pain, or, in severe cases, irregular heartbeat. If you encounter any adverse effects after taking diosmin, discontinue use and consult a healthcare provider. Seek immediate medical attention if you experience severe pain, severe diarrhea (10 or more loose stools in 24 hours), or an irregular heartbeat.

Dosage and How to Take

Diosmin is widely available over the counter and is typically sold as micronized purified flavonoid fraction (MPFF), containing 90% diosmin and 10% hesperidin. One of the most commonly used diosmin supplements is Daflon 500, which consists of 450 mg of diosmin and 50 mg of hesperidin. It may also be known as Detralex in certain regions. However, there are several other diosmin products available in pharmacies and online stores.

Want to prevent your piles surgery?

The Piles Matrix Kit has been found effective in treating grade-1 to grade-4 piles at home and has prevented over 50,000+ piles surgeries.

Buy Now

Buy Now

The recommended dosage for diosmin is typically one 500 mg supplement taken with food in the morning and another in the evening, totaling 1,000 mg per day. These dosage guidelines have been shown to be safe and effective for various conditions, such as chronic venous disease, Piles, and varicose veins.

For chronic venous disease, it is recommended to take 1,000 mg of diosmin per day for a period of 3-6 months. In the case of Piles, a dosage of 1,000-2,000 mg per day for 4 days, followed by 1,000 mg per day for 3 days, is suggested. For varicose veins, a daily dosage of 1,000-2,000 mg can be taken for up to 6 months.

It's important to adhere to the recommended dosage and not exceed the duration of use unless specifically advised by a healthcare professional.

Overdose

To date, there have been no reported cases of diosmin overdose or toxicity. Nevertheless, it is always essential to follow the instructions on the label and consult a healthcare professional to ensure the correct usage and dosage for your specific needs.

Interactions

Diosmin may interact with certain medications, including anticoagulants (such as Warfarin), anticonvulsants (such as Carbamazepine and Phenytoin/Dilantin), antihistamines (such as Allegra), muscle relaxants (such as Chlorzoxazone), non-steroidal anti-inflammatory drugs (such as Voltaren, Motrin, Advil, and Aleve), and acetaminophen (such as Tylenol). These interactions can potentially reduce the effectiveness of medications or interfere with proper blood clotting.

Additionally, diosmin may interact with certain herbal supplements, including fenugreek, feverfew, garlic, ginger, ginkgo, ginseng, and turmeric, due to their involvement in blood thinning.

If you are taking any of these medications or supplements, it is crucial to consult your healthcare provider before incorporating diosmin into your routine.

Storage and Handling

Diosmin should be stored in a cool and dry environment, such as a medicine cabinet. Always read the label and avoid consuming any supplements past their expiration date.

Pregnancy and Breastfeeding

Due to a lack of safety research, it is advisable for pregnant or breastfeeding women to avoid taking diosmin. It is always recommended to consult with a healthcare provider before taking any supplements or medications during pregnancy or while breastfeeding.

Use in Specific Populations

Individuals with bleeding disorders should exercise caution when considering diosmin supplementation, as it may worsen bleeding. It is important to consult a healthcare provider before taking diosmin if you have a bleeding disorder.

Furthermore, diosmin is not recommended for children and teenagers due to insufficient safety research in these age groups.

If you have any underlying conditions such as diabetes, heart disease, or inflammatory bowel disease (IBD), it is crucial to consult with your healthcare provider before starting diosmin supplementation. They can provide personalized advice based on your specific health needs and potential interactions with other medications you may be taking.

Side Effects

Diosmin is generally well-tolerated, and serious side effects are rare. However, some individuals may experience mild and temporary side effects, including gastrointestinal disturbances such as nausea, stomach discomfort, or diarrhea. These side effects are typically mild and resolve on their own without the need for medical intervention.

In very rare cases, allergic reactions to diosmin may occur. If you experience symptoms such as rash, itching, swelling, dizziness, or difficulty breathing, it is important to seek immediate medical attention.

Conclusion

Diosmin is a flavonoid compound with potential health benefits for conditions such as chronic venous disease, Piles, and varicose veins. It is available over the counter in various formulations, with the most common being Daflon 500 or Detralex.

When taking diosmin, it is important to follow the recommended dosage and consult with your healthcare provider, especially if you have underlying health conditions or are taking other medications. While diosmin is generally considered safe, it may interact with certain medications and supplements, and individual responses can vary.

If you experience any concerning symptoms or have questions about diosmin or its usage, it is always best to consult with a healthcare professional for personalized guidance. They can assess your specific situation and provide the most appropriate recommendations for your health.